Description

Key Benefits

• High analytical sensitivity and reproducibility due to ECL technology, ideal for critical markers like troponin T, PTH, hCG, CK‑MB ([search8],[search2])
• Fast STAT turnaround—9 minutes for emergency assays such as troponin, CK‑MB, myoglobin, hCG and PTH ([search8],[search2])
• Carry-over-free pipetting with disposable tips and cups; automated sample rerun and STAT priority settings simplify workflow ([search0],[search1])
• Error‑free reagent handling with cobas® e reagent packs, closed lids, and calibration by barcode scanning (“programming by loading”) ([search0],[search1])
• Over 25,000 systems installed worldwide with >99% uptime and minimal maintenance time ([search0],[search1])

Core Features & Specifications

• Throughput: up to 86 tests per hour; supports up to 18 simultaneous assays via 18 reagent slots ([search0],[search1])
• Sample volume: 10–50 µL per test depending on assay protocol ([search0],[search5])
• Sample types: Serum, plasma, urine, others; sample handling with disk (30 positions) or rack (up to 75 samples) configuration ([search5],[search8])
• Sample container support: primary tubes (5–10 mL, 16×100 etc.), cup-on-tube options input via barcode scanning ([search5])
• Sample integrity detection: clot detection (pressure sensor), liquid level detection; disposable probe tips avoid carryover ([search5])
• Control unit: Embedded Windows XP panel PC with touchscreen user interface ([search5])
• Calibration: Lot-level and reagent-pack calibration; QC modes include individual, cumulative, preventive QC after calibration ([search5],[search3])
• Data storage capacity: up to 2,000 test and QC records; retentive storage for up to 300 reagent packs and 100 operator IDs ([search3],[search5])
• Connectivity: RS-232 bidirectional, USB, Ethernet support for LIMS integration ([search7],[search3])
• Power: AC 100–240 V, consumption around 1,000 VA ([search5],[search7])
• Water & waste: Onboard water (~3 L) and waste container (4 L) or direct drain; water quality <10 μS/cm bacterial free ([search5],[search3])
• Operating environment: Temperature 18–32 °C; humidity 20–80% non-condensing; noise output 60 dBA standby, 63 dBA operation ([search5],[search3])
• Dimensions & Weight: Disk: approx. 120–170 cm (W) × 73–95 cm (D) × 56 cm (H), ~180 kg; Rack: up to ~210 kg ([search3],[search4])

Recommended Use Cases

• Small to medium-sized laboratories performing 50–250 immunoassay tests per day
• Clinical, cardiac, endocrinology, fertility, tumor marker, and infectious disease testing applications ([search2],[search8])
• Emergency STAT testing environments prioritizing fast turnaround
• Facilities requiring high reliability and established uptime

Additional Information

• Supports pre-defined assay protocols (sandwich, competitive, titration) with barcode-based reagent programming ([search5])
• Memory supports rerun, repeat, reflex actions; up to 100 controls pre-programmable ([search3])
• Maintenance issues reported by users—requires standby for reagent loading and troubleshooting; user experiences vary depending on service infrastructure :contentReference[oaicite:1]{index=1}
• Criticisms around UI and inflexible software flow—some labs find daily QC and navigation sluggish or unintuitive :contentReference[oaicite:2]{index=2}

Summary

The cobas® e 411 analyzer is a robust and sensitive immunoassay platform built on ECL technology, offering high throughput, fast STAT response, and reliable reagent handling. Ideal for moderate-volume clinical and hospital labs seeking versatile assay capability across multiple disciplines. Users should factor in platform-specific maintenance workflows and UI considerations.